Chemotherapy and Its Side Effects: Chapter 2 - Mitotic ihibitors (Tubule inhibitors)(Cont'd)

C.2. Vinblastine

Fig. 1.10  Vinblastine

Vinblastine (Fig. 1.10) was first isolated from a Madagascar plant, periwinkle. Vinblastine has been used to treat Hodgkin’s lymphoma, lung cancer, and bladder cancer. It works as a mitotic inhibitor, similar to Paclitaxel through microtubule modulation by suppressing microtubule dynamics and the reduction microtubule mass.

© Jiajiu Shaw, 2019

Disclaimer: This blog is written solely for informational purposes. It does not constitute the practice of any medical, nursing or other medical professional health care advice, diagnosis, or treatment. All contents posted are extracted from the book, "SIDE EFFECTS OF CHEMOTHERAPY AND RADIOTHERAPY", prepared by Dr. Jiajiu Shaw, Dr. Frederick Valeriote, and Dr. Ben Chen.