Many
natural products have been used in preventing or treating different
diseases. However, is it possible to prevent
or even treat cancer by natural products?
The short answer may be “Yes” but the more practical answer is “Depending
on many factors, certain natural products might be helpful in cancer treatment.” Nevertheless, please keep in mind that before
any natural product can be called a drug, it must first be approved by the Food
and Drug Administration (FDA).
As a background of this section, let’s clarify some
important points. First, there is not a
single approved drug that works on all types of cancer, not to mention a
natural product. The best one can say is
that some natural products might be effective in the prevention or treatment of
some cancer under certain conditions. Furthermore, there is no guarantee that the
same drug will work on the same cancer for all patients. This is because human being is a complex
organism and the same cancer in different patients could be somewhat different
and the treatment may have to be modified accordingly.
Secondly, every natural product contains multiple
ingredients; some are active and most are inactive. Depending on the manufactures of the natural
products, the ingredients could be significantly different. This is different from the drugs approved by
the FDA in that the active ingredient(s) are exactly the same, no matter which
companies make the drug products.
Therefore, it is important to distinguish the differences between FDA
approved drugs and natural products.
Keep in mind, an active ingredient in certain natural product, as a pure
pharmaceutical active ingredient (API), can be developed to become a new
drug. At that time, it will be called a
“new drug” and not referred to as a natural product.
Although
some natural products may show anti-cancer effects in vitro, there are two important points to keep in mind:
·
Just because something shows positive anti-cancer
effect in vitro (i.e., outside a
living organism), it does not mean that the compound will be effective in vivo (i.e., within a living
organism).
·
Even
if some natural compound in certain natural product is effective against the
growth of cancer cell in vivo, it may
take a lot of the natural product to really show the anticancer effect in real
life.
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